CQRZ medical Co., Ltd. uses tantalum as a material to develop a new type of porous tantalum artificial bone, which will not degrade after implantation in the human body, will not form a separation interface with bone tissue, and will not cause inflammation with surrounding tissue Sexual reactions may be corroded and dissolved by surrounding tissues to produce looseness. Its porous nature can also make the host's bone tissue three-dimensionally regenerate in the pores of the artificial bone, becoming "living reinforced concrete-type reconstructed bone".
The reporter learned that more than one million patients in China need to implant bone repair materials every year, and the market size is hundreds of billions of yuan. At present, bone repair materials are mainly dense medical titanium alloy products, but for large segment and segmental bone loss with large bone loss, this technique cannot be repaired.
"Is there a metal material that can be compatible with the human body instead of the fixation and support of titanium alloys, and can also replace or repair large segment or segmental bone loss with large bone mass?" Ye Lei, general manager of Runze Medicine said , CQRZ medical's R & D team thought of metal tantalum. However, it is extremely difficult to process dense metal tantalum into porous tantalum. Before CQRZ medical developed porous tantalum artificial bone, only one company in the world was able to manufacture porous tantalum metal bone trabeculae.
In 2007, CQRZ medical started research on porous tantalum artificial bone, and cooperated with the Institute of Metal Research of the Chinese Academy of Sciences, Southwest Hospital of Army Military Medical University, Xijing Hospital of Air Force Military Medical University, and the First Affiliated Hospital of Chongqing Medical University to establish a project team after more than 10 years of concentration Research, successfully developed a multi-stage porous tantalum material that can be used for artificial bone.
Ye Lei said that there are currently only CQRZ medical in the world who have mastered the manufacturing technology of multi-stage porous tantalum materials.
Compared with single-stage porous tantalum materials, the physical properties of multi-stage porous tantalum materials have changed. They have sponge-like "wetting characteristics", which can guide bone tissue through body fluids into artificial bone pores, where they can grow and develop. Artificial bones have become "living reinforced concrete-type reconstructed bones". Substantial development of large-segment and segmental bone-loss repair materials with bone support, bone regeneration and bone fusion properties has been subversively developed.
Shenyang National Research Center for Materials Science is an authoritative academic institution in the field of materials in China. Zhang Jinsong, a researcher at the center, said that the porous tantalum materials developed by Runze Pharmaceutical have huge market development potential. It is reported that the global bone repair material market currently has nearly 50 billion US dollars of "cake" each year. CQRZ medical's new material, porous tantalum artificial bone, has been successfully developed, which will not only reduce domestic dependence on imported bone repair materials, but also enter overseas markets with leading technologies. .